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16-bit Microcontrollers - MCU

16-bit Microcontrollers are in stock with same-day shipping at Mouser from industry leading manufacturers. Mouser is an authorized distributor for many 16-bit microcontroller manufacturers including Infineon, Microchip, NXP, Renesas, Texas Instruments & more.
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Image	Part #	Mfr.	Description	Datasheet	Availability	Pricing (USD) Filter the results in the table by unit price based on your quantity.	Qty.	Core	Program Memory Size	Data RAM Size	Package / Case	Maximum Clock Frequency	ADC Resolution	Number of I/Os	Supply Voltage - Min	Supply Voltage - Max	Mounting Style	Data Bus Width	Minimum Operating Temperature	Maximum Operating Temperature	Series	Qualification	Packaging
16-bit Microcontrollers - MCU Mixed Signal Microco ntroller MSP430F5438AMPZREP Texas Instruments 1: $23.18 1,354In Stock	Mfr. Part # MSP430F5438AMPZREP Mouser Part # 595-P430F5438AMPZREP	Texas Instruments	16-bit Microcontrollers - MCU Mixed Signal Microco ntroller Learn More about Texas Instruments ti msp430 mcus This product may require additional documentation to export from the United States.	Datasheet	1,354In Stock	Cut Tape $23.18 $18.43 $16.69 $16.01 View Reel $15.14 $15.70 $15.28 $15.14 Quote MouseReel Available	Min.: 1 Mult.: 1 : 1,000	MSP430	256 kB	16 kB	LQFP-100	25 MHz	12 bit	87 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 55 C	+ 125 C	MSP430F5438A		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 24-MHz 105-C integra ted analog microcon A 595-SP430FR2355TRSMT MSP430FR2355TRSMR Texas Instruments 1: $4.60 A tariff of 38% may be applied if shipping to the United States. 9,011In Stock 12,000Expected 1/21/2027	Mfr. Part # MSP430FR2355TRSMR Mouser Part # 595-SP430FR2355TRSMR	Texas Instruments	16-bit Microcontrollers - MCU 24-MHz 105-C integra ted analog microcon A 595-SP430FR2355TRSMT Learn More about Texas Instruments ti msp430fr215 msp430fr235 mcus	Datasheet	9,011In Stock 12,000Expected 1/21/2027	Cut Tape $4.60 $3.49 $3.05 $2.91 $2.69 Reel $2.69 MouseReel Available A tariff of 38% may be applied if shipping to the United States.	Min.: 1 Mult.: 1 : 3,000	MSP430	16 kB	32 kB	VQFN-32	24 MHz	12 bit	28 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 105 C	MSP430FR2355		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 16MHz Ultra-Low-Pwr MCU A 595-SP430FR596 A 595-SP430FR5969IRGZT MSP430FR5969IRGZR Texas Instruments 1: $7.79 3,702In Stock 10,000Expected 1/4/2027	Mfr. Part # MSP430FR5969IRGZR Mouser Part # 595-SP430FR5969IRGZR	Texas Instruments	16-bit Microcontrollers - MCU 16MHz Ultra-Low-Pwr MCU A 595-SP430FR596 A 595-SP430FR5969IRGZT Learn More about Texas Instruments ti msp430fr5969	Datasheet	3,702In Stock 10,000Expected 1/4/2027	Cut Tape $7.79 $6.01 $5.29 $4.97 $4.61 Reel $4.37 MouseReel Available	Min.: 1 Mult.: 1 : 2,500	MSP430	64 kB	2 kB	VQFN-48	16 MHz	12 bit	40 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430FR5969		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU Mixed Signal MCU A 5 95-MSP430G2553IPW20 A 595-MSP430G2553IPW20 MSP430G2553IPW20R Texas Instruments 1: $5.55 13,433In Stock 32,000Expected 3/15/2027	Mfr. Part # MSP430G2553IPW20R Mouser Part # 595-SP430G2553IPW20R	Texas Instruments	16-bit Microcontrollers - MCU Mixed Signal MCU A 5 95-MSP430G2553IPW20 A 595-MSP430G2553IPW20 Learn More about Texas Instruments ti msp430g2 mcus	Datasheet	13,433In Stock 32,000Expected 3/15/2027	Cut Tape $5.55 $3.67 $3.35 $2.84 View Reel $2.04 $2.70 $2.42 $2.41 $2.04 MouseReel Available	Min.: 1 Mult.: 1 : 2,000	MSP430	16 kB	512 B	TSSOP-20	16 MHz	10 bit	16 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430G2553		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU S12A 16-bit MCU, HCS12 core, 64KB Flash, QFP 80 MC9S12A64CFUE NXP Semiconductors 1: $32.34 1,560In Stock	Mfr. Part # MC9S12A64CFUE Mouser Part # 841-MC9S12A64CFUE	NXP Semiconductors	16-bit Microcontrollers - MCU S12A 16-bit MCU, HCS12 core, 64KB Flash, QFP 80	Datasheet	1,560In Stock	$32.34 $26.17 $25.93 View Quote	Min.: 1 Mult.: 1	HCS12	64 kB	4 kB	QFP-80	25 MHz	10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12A		Tray
16-bit Microcontrollers - MCU S12C 16-bit MCU, HCS12 core, 128KB Flash, QFP 48 MC9S12C128MFAE NXP Semiconductors 1: $43.13 749In Stock	Mfr. Part # MC9S12C128MFAE Mouser Part # 841-MC9S12C128MFAE	NXP Semiconductors	16-bit Microcontrollers - MCU S12C 16-bit MCU, HCS12 core, 128KB Flash, QFP 48	Datasheet	749In Stock	$43.13 $35.83 $33.99 $32.52 View $32.19 Quote	Min.: 1 Mult.: 1	HCS12	128 kB	4 kB	LQFP-48	25 MHz	10 bit	31 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12C		Tray
16-bit Microcontrollers - MCU S12C 16-bit MCU, HCS12 core, 64KB Flash, QFP 48 MC9S12C64CFAE NXP Semiconductors 1: $34.07 1,714In Stock	Mfr. Part # MC9S12C64CFAE Mouser Part # 841-MC9S12C64CFAE	NXP Semiconductors	16-bit Microcontrollers - MCU S12C 16-bit MCU, HCS12 core, 64KB Flash, QFP 48	Datasheet	1,714In Stock	$34.07 $27.61 $25.03 $24.23 View $24.09 $23.93 Quote	Min.: 1 Mult.: 1	HCS12	64 kB	4 kB	LQFP-48	25 MHz	10 bit	31 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12C		Tray
16-bit Microcontrollers - MCU S12D 16-bit MCU, HCS12 core, 64KB Flash, QFP 80 MC9S12D64CFUE NXP Semiconductors 1: $46.71 2,039In Stock 1,680Expected 11/30/2026	Mfr. Part # MC9S12D64CFUE Mouser Part # 841-MC9S12D64CFUE	NXP Semiconductors	16-bit Microcontrollers - MCU S12D 16-bit MCU, HCS12 core, 64KB Flash, QFP 80	Datasheet	2,039In Stock 1,680Expected 11/30/2026	$46.71 $36.35 $34.24 $34.07 View Quote	Min.: 1 Mult.: 1	HCS12	64 kB	4 kB	PQFP-80	25 MHz	2 x 10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12D		Tray
16-bit Microcontrollers - MCU S12DG 16-bit MCU, HCS12 core, 128KB Flash, QFP 80 MC9S12DG128CFUER NXP Semiconductors 1: $55.68 497In Stock 750Expected 11/25/2026	Mfr. Part # MC9S12DG128CFUER Mouser Part # 841-MC9S12DG128CFUER	NXP Semiconductors	16-bit Microcontrollers - MCU S12DG 16-bit MCU, HCS12 core, 128KB Flash, QFP 80	Datasheet	497In Stock 750Expected 11/25/2026	Cut Tape $55.68 $45.76 $43.16 $41.78 $40.55 Reel $40.54 MouseReel Available	Min.: 1 Mult.: 1 : 750	HCS12	128 kB	8 kB	PQFP-80	50 MHz	2 x 10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12D		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU S12DG 16-bit MCU, HCS12 core, 256KB Flash, QFP 112 MC9S12DG256CPVE NXP Semiconductors 1: $73.33 638In Stock	Mfr. Part # MC9S12DG256CPVE Mouser Part # 841-MC9S12DG256BCP	NXP Semiconductors	16-bit Microcontrollers - MCU S12DG 16-bit MCU, HCS12 core, 256KB Flash, QFP 112	Datasheet	638In Stock	$73.33 $61.02 $60.48 $56.66 View Quote	Min.: 1 Mult.: 1	HCS12	256 kB	12 kB	LQFP-112	25 MHz	2 x 10 bit	91 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12D		Tray
16-bit Microcontrollers - MCU S12DG 16-bit MCU, HCS12 core, 256KB Flash, QFP 80 MC9S12DG256CFUE NXP Semiconductors 1: $71.19 277In Stock	Mfr. Part # MC9S12DG256CFUE Mouser Part # 841-MC9S12DG256CFUE	NXP Semiconductors	16-bit Microcontrollers - MCU S12DG 16-bit MCU, HCS12 core, 256KB Flash, QFP 80	Datasheet	277In Stock	$71.19 $58.94 $57.08 $55.68 View Quote	Min.: 1 Mult.: 1	HCS12	256 kB	12 kB	PQFP-80	25 MHz	2 x 10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12D		Tray
16-bit Microcontrollers - MCU S12DP 16-bit MCU, HCS12 core, 512KB Flash, QFP 112 MC9S12DP512CPVE NXP Semiconductors 1: $52.37 564In Stock	Mfr. Part # MC9S12DP512CPVE Mouser Part # 841-MC9S12DP512CPVE	NXP Semiconductors	16-bit Microcontrollers - MCU S12DP 16-bit MCU, HCS12 core, 512KB Flash, QFP 112	Datasheet	564In Stock	$52.37 $51.04 $49.08 $47.28 View Quote	Min.: 1 Mult.: 1	HCS12	512 kB	14 kB	LQFP-112	25 MHz	2 x 10 bit	91 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12D		Tray
16-bit Microcontrollers - MCU S12DP 16-bit MCU, HCS12 core, 512KB Flash, QFP 112 MC9S12DP512MPVE NXP Semiconductors 1: $60.35 478In Stock	Mfr. Part # MC9S12DP512MPVE Mouser Part # 841-MC9S12DP512MPVE	NXP Semiconductors	16-bit Microcontrollers - MCU S12DP 16-bit MCU, HCS12 core, 512KB Flash, QFP 112	Datasheet	478In Stock	$60.35 $49.75 Quote Quote	Min.: 1 Mult.: 1	HCS12	512 kB	14 kB	LQFP-112	25 MHz	2 x 10 bit	91 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12D		Tray
16-bit Microcontrollers - MCU S12DT 16-bit MCU, HCS12 core, 256KB Flash, QFP 112 MC9S12DT256CPVE NXP Semiconductors 1: $79.67 613In Stock	Mfr. Part # MC9S12DT256CPVE Mouser Part # 841-MC9S12DT256CPVE	NXP Semiconductors	16-bit Microcontrollers - MCU S12DT 16-bit MCU, HCS12 core, 256KB Flash, QFP 112	Datasheet	613In Stock	$79.67 $67.57 $63.00 $62.69 View Quote	Min.: 1 Mult.: 1	HCS12	256 kB	12 kB	LQFP-112	25 MHz	2 x 10 bit	91 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12D		Tray
16-bit Microcontrollers - MCU S12XD 16-bit MCU, HCS12X core, 512KB Flash, 80MHz, QFP 144 MC9S12XDP512CAG NXP Semiconductors 1: $51.91 428In Stock	Mfr. Part # MC9S12XDP512CAG Mouser Part # 841-MC9S12XDP512CAG	NXP Semiconductors	16-bit Microcontrollers - MCU S12XD 16-bit MCU, HCS12X core, 512KB Flash, 80MHz, QFP 144	Datasheet	428In Stock	$51.91 $42.61 $38.88 $37.73 Quote Quote	Min.: 1 Mult.: 1	HCS12X	512 kB	32 kB	LQFP-144	80 MHz	10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12XD		Tray
16-bit Microcontrollers - MCU S12XD 16-bit MCU, HCS12X core, 512KB Flash, 80MHz, QFP 112 MC9S12XDP512CAL NXP Semiconductors 1: $57.26 1,169In Stock	Mfr. Part # MC9S12XDP512CAL Mouser Part # 841-MC9S12XDP512CAL	NXP Semiconductors	16-bit Microcontrollers - MCU S12XD 16-bit MCU, HCS12X core, 512KB Flash, 80MHz, QFP 112	Datasheet	1,169In Stock	$57.26 $47.14 $43.08 $41.26 View Quote	Min.: 1 Mult.: 1	HCS12X	512 kB	32 kB	LQFP-112	80 MHz	10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12XD		Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 1MB Flash, 50MHz, -40/+85degC, QFP 144 MC9S12XEP100CAG NXP Semiconductors 1: $50.98 897In Stock	Mfr. Part # MC9S12XEP100CAG Mouser Part # 841-MC9S12XEP100CAG	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 1MB Flash, 50MHz, -40/+85degC, QFP 144	Datasheet	897In Stock	$50.98 $42.27 $39.96 $38.63 View Quote	Min.: 1 Mult.: 1	HCS12X	1 MB	64 kB	LQFP-144	50 MHz	2 x 8 bit/10 bit/12 bit	119 I/O	1.72 V	1.98 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12XE	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 512KB Flash, 50MHz, -40/+85degC, QFP 80 MC9S12XEQ512CAA NXP Semiconductors 1: $38.66 840In Stock	Mfr. Part # MC9S12XEQ512CAA Mouser Part # 841-MC9S12XEQ512CAA	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 512KB Flash, 50MHz, -40/+85degC, QFP 80	Datasheet	840In Stock	$38.66 $32.56 $31.10 $27.81 View $27.14 $26.80 Quote	Min.: 1 Mult.: 1	HCS12X	512 kB	32 kB	QFP-80	50 MHz	2 x 8 bit/10 bit/12 bit	59 I/O	1.72 V	1.98 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12XE	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 512KB Flash, 50MHz, -40/+125degC, QFP 144 MC9S12XEQ512MAG NXP Semiconductors 1: $42.19 110In Stock	Mfr. Part # MC9S12XEQ512MAG Mouser Part # 841-MC9S12XEQ512MAG	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 512KB Flash, 50MHz, -40/+125degC, QFP 144	Datasheet	110In Stock	$42.19 $34.64 $33.53 $31.41 View $29.37 Quote	Min.: 1 Mult.: 1	HCS12X	512 kB	32 kB	LQFP-144	50 MHz	2 x 8 bit/10 bit/12 bit	119 I/O	1.72 V	1.98 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12XE	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 256KB Flash, 50MHz, -40/+125degC, QFP 112 MC9S12XET256MAL NXP Semiconductors 1: $29.62 1,100In Stock	Mfr. Part # MC9S12XET256MAL Mouser Part # 841-MC9S12XET256MAL	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 256KB Flash, 50MHz, -40/+125degC, QFP 112	Datasheet	1,100In Stock	$29.62 $23.91 $21.61 $20.90 View $20.03 Quote	Min.: 1 Mult.: 1	HCS12X	256 kB	16 kB	LQFP-112	50 MHz	2 x 8 bit/10 bit/12 bit	91 I/O	1.98 V	1.72 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12XE	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 128KB Flash, 40MHz, -40/+125degC, QFP 80 MC9S12XS128MAA NXP Semiconductors 1: $23.95 326In Stock	Mfr. Part # MC9S12XS128MAA Mouser Part # 841-MC9S12XS128MAA	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 128KB Flash, 40MHz, -40/+125degC, QFP 80	Datasheet	326In Stock	$23.95 $19.35 $18.55 $16.34 View $14.41 $14.37 $14.12 Quote	Min.: 1 Mult.: 1	HCS12	128 kB	8 kB	PQFP-80	40 MHz	12 bit	91 I/O	1.72 V	1.98 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12XS	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU_RL78/F13_64KB 20SSOP R5F10A6EKSP#U5 Renesas Electronics 1: $5.67 722In Stock	Mfr. Part # R5F10A6EKSP#U5 Mouser Part # 968-R5F10A6EKSP#U5	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU_RL78/F13_64KB 20SSOP Learn More about Renesas Electronics renesas rl78 automotive mcus	Datasheet	722In Stock	$5.67 $3.90 $3.63 $3.14 View $3.02 $2.71 $2.54 $2.53 Quote	Min.: 1 Mult.: 1	RL78	64 kB	4 kB	SSOP-20	24 MHz	10 bit	13 I/O	2.7 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 125 C	RL78/F13	AEC-Q100	Tray
16-bit Microcontrollers - MCU 32KB Flash 1KB RAM S igDelt ADC/128 sLCD A 595-430F427IPM MSP430F427IPMR Texas Instruments 1: $11.11 578In Stock NRND	Mfr. Part # MSP430F427IPMR Mouser Part # 595-430F427IPMR NRND	Texas Instruments	16-bit Microcontrollers - MCU 32KB Flash 1KB RAM S igDelt ADC/128 sLCD A 595-430F427IPM Learn More about Texas Instruments ti msp430 mcus	Datasheet	578In Stock	Cut Tape $11.11 $8.68 $7.71 $7.41 View Reel $6.71 $6.97 $6.71 Quote MouseReel Available	Min.: 1 Mult.: 1 : 1,000	MSP430	32 kB	1 kB	LQFP-64	16 MHz	16 bit	14 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430F427		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU MCU 3/5V 32+2K Pbfree 32LQFP T&R R5F21276SNFP#X6 Renesas Electronics 1: $13.52 A tariff of 38% may be applied if shipping to the United States. 444In Stock NRND	Mfr. Part # R5F21276SNFP#X6 Mouser Part # 968-R5F21276SNFP#X6 NRND	Renesas Electronics	16-bit Microcontrollers - MCU MCU 3/5V 32+2K Pbfree 32LQFP T&R	Datasheet	444In Stock	Cut Tape $13.52 $10.64 $9.48 $9.12 View Reel $8.29 $8.97 $8.60 $8.29 Quote A tariff of 38% may be applied if shipping to the United States.	Min.: 1 Mult.: 1 : 1,000														R8C/27		Reel, Cut Tape
16-bit Microcontrollers - MCU 16 Bit 128KB Flash 8Kb RAM 53 I/O PIC24FJ128GA008-I/PT Microchip Technology 1: $5.34 1,309In Stock	Mfr. Part # PIC24FJ128GA008-I/PT Mouser Part # 579-24FJ128GA008IPT	Microchip Technology	16-bit Microcontrollers - MCU 16 Bit 128KB Flash 8Kb RAM 53 I/O Learn More about Microchip Technology microchip pic24fj	Datasheet	1,309In Stock	$5.34 $4.89 $4.83	Min.: 1 Mult.: 1	PIC24F	128 kB	8 kB	TQFP-80	32 MHz	10 bit	69 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGA008		Tray